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Western blot analysis of extracts of K562 cells using TPMT Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of K562 cells using TPMT Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of K562 cells using TPMT Polyclonal Antibody at dilution of 1:1000.

TPMT Polyclonal Antibody

E-AB-60140
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    TPMT Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
  • UNSPSC
    12352203