IHC-P analysis of thyroid, Graves disease tissue using GTX01955 TPO antibody [AC25]. Note intense cytoplasmic staining of thyroid epithelial cells.
IHC-P analysis of thyroid, Graves disease tissue using GTX01955 TPO antibody [AC25]. Note intense cytoplasmic staining of thyroid epithelial cells.
TPO antibody [AC25]
GTX01955
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTPO
Overview
- SupplierGeneTex
- Product NameTPO antibody [AC25]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:80. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAC25
- ConjugateUnconjugated
- Gene ID7173
- Target nameTPO
- Target descriptionthyroid peroxidase
- Target synonymsMSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; TPX
- HostMouse
- IsotypeIgG1
- Protein IDP07202
- Protein NameThyroid peroxidase
- Scientific DescriptionThis gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203