TPP1 blocking peptide

GeneTex

TPP1 blocking peptide

9

Research Use Only

TPP1

tripeptidyl peptidase 1

CLN2, GIG1, LPIC, SCAR7, TPP-1, tripeptidyl-peptidase 1, cell growth-inhibiting gene 1 protein, growth-inhibiting protein 1, lysosomal pepstatin insensitive protease, lysosomal pepstatin-insensitive carboxypeptidase, tripeptidyl aminopeptidase, tripeptidyl peptidase I

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

41116100

Human