TPX-0022(CSF1R-IN-2)

Biorbyt

TPX-0022(CSF1R-IN-2) [2271119-26-5]

10

2271119-26-5

Research Use Only

C20H20FN7O2

409.425

TPX-0022 (CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.

FC1C=CC2=C(C=1C#N)CN(CC)C1C=CN3C(=C(C(N)=N3)C(NC[C@H](C)O2)=O)N=1

12352200