TRADD antibody

GeneTex

TRADD antibody

9

WB: 1:500-1:1000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

TRADD

TNFRSF1A associated via death domain

Hs.89862, tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated death domain protein, tumor necrosis factor receptor type 1 associated death domain protein, tumor necrosis factor receptor-1-associated protein

Rabbit

IgG

Tumor necrosis factor receptor type 1-associated DEATH domain protein

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

41116161