TRAF-STOP inhibitor 6877002

MedChem Express

TRAF-STOP inhibitor 6877002 [433249-94-6]

10

433249-94-6

Research Use Only

99.67

C17H17NO

251.32

TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-kappaB pathway[1].

O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C

-20°C,2°C to 8°C

12352200