TRAF-STOP inhibitor 6877002

MedChem Express

TRAF-STOP inhibitor 6877002 [433249-94-6]

10

433249-94-6

Research Use Only

99.67

C17H17NO

251.32

TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction, compound VII, shows inhibition of NF-kappaB activation in RAW cells, extracted from patent WO2014033122A1. TRAF-STOP 6877002 prevents the progression of established atherosclerosis in mice, reduces leukocyte recruitment and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques [1] [2] .

O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C

-20°C,2°C to 8°C

12352200