TRAF4 antibody, Internal

GeneTex

TRAF4 antibody, Internal

9

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

TRAF4

TNF receptor associated factor 4

CART1; cysteine-rich domain associated with ring and TRAF domain; cysteine-rich domain associated with RING and Traf domains protein 1; malignant 62; metastatic lymph node gene 62 protein; MLN 62; MLN62; RING finger protein 83; RNF83; TNF receptor-associated factor 4; TRAF4 variant 6; tumor necrosis receptor-associated factor 4A

Rabbit

IgG

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C,-20°C or -80°C

12352203