TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

TargetMol Chemicals

TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

16

Research Use Only

Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesnt transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.

-20°C

12352202