TRAIL/TNFSF10, Rhesus Macaque

MedChem Express

TRAIL/TNFSF10, Rhesus Macaque

10

Research Use Only

97.40

TNFSF10

TNF superfamily member 10

TNLG6A, tumor necrosis factor ligand superfamily member 10, tumor necrosis factor (ligand) superfamily, member 10, tumor necrosis factor ligand 6A, tumor necrosis factor superfamily member 10

Tumor necrosis factor ligand superfamily member

TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways[1][2]. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell[1]. TRAIL/TNFSF10 Protein, Rhesus Macaque is a recombinant Rhesus Macaque TRAIL (V114-G281) without any tag, which is expressed in E. coli.

-20°C

41116100

Primate