TRalpha-GAL4 Luciferase Reporter HEK293 Cell Line (Thyroid Hormone Receptor alpha Pathway)

BPS Bioscience

TRalpha-GAL4 Luciferase Reporter HEK293 Cell Line (Thyroid Hormone Receptor alpha Pathway)

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Research Use Only

The TRalpha-GAL4 Luciferase Reporter HEK293 Cell Line is a HEK293 cell line expressing firefly luciferase under the control of the GAL4 upstream activation sequence (UAS) with constitutive expression of human thyroid receptor alpha ligand binding domain fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD). This system allows specific detection of thyroid hormone-induced activation of the thyroid receptor alpha with low cross-reactivity from other nuclear receptors. This cell line has been validated by stimulation with triiodothyronine (T-3).

Liquid Nitrogen

12352207