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Trametinib (DMSO solvate)

Research Use Only
HY-10999A
MedChem Express
CAS Number1187431-43-1
Product group Chemicals
Estimated Purity99.74
Molecular Weight693.53
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Trametinib (DMSO solvate) [1187431-43-1]
  • Delivery Days Customer
    10
  • CAS Number
    1187431-43-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.74
  • Molecular Formula
    C28H29FIN5O5S
  • Molecular Weight
    693.53
  • Scientific Description
    Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis[1][2].
  • SMILES
    CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200