Trametinib (DMSO solvate)
HY-10999A
CAS Number1187431-43-1
Product group Chemicals
Estimated Purity99.74
Molecular Weight693.53
Overview
- SupplierMedChem Express
- Product NameTrametinib (DMSO solvate) [1187431-43-1]
- Delivery Days Customer10
- CAS Number1187431-43-1
- CertificationResearch Use Only
- Estimated Purity99.74
- Molecular FormulaC28H29FIN5O5S
- Molecular Weight693.53
- Scientific DescriptionTrametinib (DMSO solvate) (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis[1][2].
- SMILESCN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200