ProductsBack/Transgelin 2 antibody [N1C3]

Transgelin 2 antibody [N1C3]

Name: Transgelin 2 antibody [N1C3]
SKU: GTX115082_G10
Availability: BackOrder

GTX115082

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetTAGLN2

Overview

Supplier
GeneTex
Product Name
Transgelin 2 antibody [N1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.53 mg/ml
Conjugate
Unconjugated
Gene ID8407
Target name
TAGLN2
Target description
transgelin 2
Target synonyms
HA1756, transgelin-2, SM22-alpha homolog, epididymis secretory sperm binding protein, epididymis tissue protein Li 7e
Host
Rabbit
Isotype
IgG
Protein IDP37802
Protein Name
Transgelin-2
Scientific Description
The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Girard CA, Lecacheur M, Ben Jouira R, et al. A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma. Cancer Res. 2020,80(10):1927-1941. doi: 10.1158/0008-5472.CAN-19-2914
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Liu L, Meng T, Zheng X, et al. Transgelin 2 Promotes Paclitaxel Resistance, Migration, and Invasion of Breast Cancer by Directly Interacting with PTEN and Activating PI3K/Akt/GSK-3β Pathway. Mol Cancer Ther. 2019,18(12):2457-2468. doi: 10.1158/1535-7163.MCT-19-0261
Read this paper
Zheng X, Wang C, Xing Y, et al. SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells. Int J Oncol. 2017,50(3):893-902. doi: 10.3892/ijo.2017.3871
Read this paper
Cai J, Chen S, Zhang W, et al. Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2. Phytomedicine. 2014,21(7):984-91. doi: 10.1016/j.phymed.2014.02.012
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Chen S, Dong Q, Hu S, et al. Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells. Mol Biosyst. 2014,10(2):294-303. doi: 10.1039/c3mb70428a
Read this paper