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ProductsBack/Transgelin 2 antibody [N1C3]

Transgelin 2 antibody [N1C3]

GTX115082
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetTAGLN2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Transgelin 2 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.53 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8407
  • Target name
    TAGLN2
  • Target description
    transgelin 2
  • Target synonyms
    epididymis secretory sperm binding protein; epididymis tissue protein Li 7e; HA1756; SM22-alpha homolog; transgelin-2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP37802
  • Protein Name
    Transgelin-2
  • Scientific Description
    The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma. Girard CA et al., 2020 May 15, Cancer Res
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  • Transgelin 2 Promotes Paclitaxel Resistance, Migration, and Invasion of Breast Cancer by Directly Interacting with PTEN and Activating PI3K/Akt/GSK-3beta Pathway. Liu L et al., 2019 Dec, Mol Cancer Ther
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  • SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells. Zheng X et al., 2017 Mar, Int J Oncol
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  • Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2. Cai J et al., 2014 Jun 15, Phytomedicine
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  • Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells. Chen S et al., 2014 Feb, Mol Biosyst
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