TRbeta-GAL4 Luciferase Reporter HEK293 Cell Line (Thyroid Hormone Receptor beta Pathway)

BPS Bioscience

TRbeta-GAL4 Luciferase Reporter HEK293 Cell Line (Thyroid Hormone Receptor beta Pathway)

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Research Use Only

The TRbeta-GAL4 Luciferase Reporter HEK293 Cell Line is a HEK293 cell line expressing firefly luciferase under the control of the GAL4 upstream activation sequence (UAS) with constitutive expression of human thyroid receptor beta ligand binding domain (TRbeta LBD, amino acids 173-461) fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD). This system allows specific detection of thyroid hormone-induced activation of the thyroid receptor beta with low cross-reactivity from other nuclear receptors. This cell line has been validated by stimulation with triiodothyronine (T-3).

Liquid Nitrogen

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