Bio-Connect

Tretazicar [21919-05-1]

HY-13543
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tretazicar [21919-05-1]
  • Delivery Days Customer
    9
  • CAS Number
    21919-05-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C9H8N4O5
  • Molecular Weight
    252.18
  • Scientific Description
    Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1)[1][2].
  • SMILES
    O=C(N)C1=CC(N2CC2)=C([N+]([O-])=O)C=C1[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    41115800