Bio-Connect

Tri-GalNAc-DBCO

HY-148476
MedChem Express
Estimated Purity99.92
Product group Chemicals
Molecular Weight1730.94
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tri-GalNAc-DBCO
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C82H127N11O29
  • Molecular Weight
    1730.94
  • Scientific Description
    Tri-GalNAc-DBCO can bind to the desialic acid glycoprotein receptor (ASGPR) to drive protein downregulation and target protein degradation, where GalNAc is a high-affinity ligand for hepatocyte-specific ASGPR [1] . Tri-GalNAc-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
  • SMILES
    O=C(NCCCNC(CCCCO[C@H](O[C@@H]1CO)[C@@H]([C@H]([C@H]1O)O)NC(C)=O)=O)CCOCC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]2CO)[C@@H]([C@H]([C@H]2O)O)NC(C)=O)=O)=O)(NC(CCCCC(N3CC4=CC=CC=C4C#CC5=CC=CC=C53)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]6CO)[C@@H]([C@H]([C@H]6O)O)NC(C)=O)=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200