TRIAP1 Antibody

Cusabio

TRIAP1 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

TRIAP1

TP53 regulated inhibitor of apoptosis 1

HSPC132; MDM35; mitochondrial distribution and morphology 35 homolog; P53CSV; p53-inducible cell-survival factor; protein 15E1.1; TP53-regulated inhibitor of apoptosis 1; WF-1

Rabbit

IgG

TP53-regulated inhibitor of apoptosis 1

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).

Human

-20°C or -80°C

41116161