Triciribine

Biorbyt

Triciribine [35943-35-2]

16

35943-35-2

Research Use Only

C13H16N6O4

320.3

Triciribine(API-2; NSC 154020) is a DNA synthesis inhibitor, also inhibits Akt and HIV-1 with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase.

OC[C@H]1O[C@@H](N2C=C3C(=NN(C4=NC=NC2=C34)C)N)[C@H](O)[C@@H]1O

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