Triclosan (Standard) [3380-34-5]
HY-B1119R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameTriclosan (Standard) [3380-34-5]
- Delivery Days Customer5
- CAS Number3380-34-5
- CertificationResearch Use Only
- Molecular FormulaC12H7Cl3O2
- Molecular Weight289.54
- Scientific DescriptionTriclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 microM and 10 microM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models[1][2][3].
- SMILESOC1=CC(Cl)=CC=C1OC2=CC=C(Cl)C=C2Cl
- UNSPSC41116135