Trifluridine/tipiracil hydrochloride mixture [733030-01-8]
HY-16478
CAS Number733030-01-8
Product group Chemicals
Estimated Purity99.98
Molecular Weight435.76
Overview
- SupplierMedChem Express
- Product NameTrifluridine/tipiracil hydrochloride mixture [733030-01-8]
- Delivery Days Customer10
- CAS Number733030-01-8
- CertificationResearch Use Only
- Estimated Purity99.98
- Molecular FormulaC10H11F3N2O5.1/2C9H11ClN4O2.1/2HCl
- Molecular Weight435.76
- Scientific DescriptionTrifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA[1][2].
- SMILESO=C1N([C@H]2C[C@H](O)[C@@H](CO)O2)C=C(C(F)(F)F)C(N1)=O.O=C3NC(CN4CCCC4=N)=C(Cl)C(N3)=O.[1/2].Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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