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Trilaciclib

HY-101467
MedChem Express
CAS Number1374743-00-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.32
Molecular Weight446.55
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Trilaciclib [1374743-00-6]
  • Delivery Days Customer
    10
  • CAS Number
    1374743-00-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.32
  • Molecular Formula
    C24H30N8O
  • Molecular Weight
    446.55
  • Scientific Description
    Trilaciclib (G1T28) is an orally active CDK4/6 inhibitor with IC 50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. . Trilaciclib can effectively inhibit tumor cell proliferation and reduce the hematological toxicity caused by chemotherapy. Trilaciclib attenuates apoptosis and myelosuppression induced by 5FU (HY-90006) chemotherapy [1] .
  • SMILES
    O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C)CC6)C=C5)N=C43)CCCCC2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200