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Trilaciclib (hydrochloride)

HY-101467A
MedChem Express
CAS Number1977495-97-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.69
Molecular Weight519.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Trilaciclib (hydrochloride) [1977495-97-8]
  • Delivery Days Customer
    9
  • CAS Number
    1977495-97-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.69
  • Molecular Formula
    C24H32Cl2N8O
  • Molecular Weight
    519.47
  • Scientific Description
    Trilaciclib (G1T28) hydrochloride is an orally active CDK4/6 inhibitor with IC 50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride can effectively inhibit tumor cell proliferation and reduce the hematological toxicity caused by chemotherapy. Trilaciclib hydrochloride attenuates apoptosis and myelosuppression induced by 5FU (HY-90006) chemotherapy [1] .
  • SMILES
    O=C1C2=CC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C=N4)N=C3N2C6(CCCCC6)CN1.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200