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TRIM32 antibody

Research Use Only
GTX113937
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetTRIM32
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Overview

  • Supplier
    GeneTex
  • Product Name
    TRIM32 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID22954
  • Target name
    TRIM32
  • Target description
    tripartite motif containing 32
  • Target synonyms
    72 kDa Tat-interacting protein; BBS11; E3 ubiquitin-protein ligase TRIM32; HT2A; LGMD2H; LGMDR8; RING-type E3 ubiquitin transferase TRIM32; TAT-interactive protein, 72-KD; TATIP; tripartite motif-containing protein 32; zinc-finger protein HT2A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13049
  • Protein Name
    E3 ubiquitin-protein ligase TRIM32
  • Scientific Description
    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • TRIM32 regulates mitochondrial mediated ROS levels and sensitizes the oxidative stress induced cell death. Prajapati P et al., 2020 Dec, Cell Signal
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  • Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling. Wang M et al., 2020 Apr, Cell Death Differ
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