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ProductsBack/TRIM37 Antibody

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA024474LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA024474LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA024474LA01HU at dilution of 1:100

TRIM37 Antibody

CSB-PA024474LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetTRIM37

Overview

Supplier
Cusabio
Product Name
TRIM37 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID4591
Target name
TRIM37
Target description
tripartite motif containing 37
Target synonyms
MUL, POB1, TEF3, E3 ubiquitin-protein ligase TRIM37, RING-B-box-coiled-coil protein, RING-type E3 ubiquitin transferase TRIM37, mulibrey nanism protein
Host
Rabbit
Isotype
IgG
Protein IDO94972
Protein Name
E3 ubiquitin-protein ligase TRIM37
Scientific Description
E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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