
Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA024474LA01HU at dilution of 1:100
TRIM37 Antibody
CSB-PA024474LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTRIM37
Overview
- SupplierCusabio
- Product NameTRIM37 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4591
- Target nameTRIM37
- Target descriptiontripartite motif containing 37
- Target synonymsMUL, POB1, TEF3, E3 ubiquitin-protein ligase TRIM37, RING-B-box-coiled-coil protein, RING-type E3 ubiquitin transferase TRIM37, mulibrey nanism protein
- HostRabbit
- IsotypeIgG
- Protein IDO94972
- Protein NameE3 ubiquitin-protein ligase TRIM37
- Scientific DescriptionE3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161





![Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with TRIM37 antibody [N1N2], N-term (GTX114565) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX114565/GTX114565_40198_20160324_WB_R_w_23060518_303.webp)