Trimegestone-13C,d3

MedChem Express

Trimegestone-13C,d3

5

Research Use Only

C21 13CH27D3O3

346.48

Trimegestone- 13 C,d 3 is 13 C and deuterated labeled Trimegestone (HY-106827). Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. Trimegestone binds to progesterone receptor (PR) with an IC 50 value of 3.3 nM (rat PR). Trimegestone increases alkaline phosphatase activity (EC 50 =0.1 nM) but not luciferase activity. Trimegestone also shows a weak antiandrogenic activity (weak androgen receptor affinity). Trimegestone can be used in studies of contraception or menopausal syndromes [1] [2] .

C[C@@]12[C@](CC[C@]2(C)C([C@@H](O)[13C]([2H])([2H])[2H])=O)([H])[C@@]3([H])C(CC1)=C4C(CC3)=CC(CC4)=O

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