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Trimipramine [739-71-9]

HY-B1213A
MedChem Express
CAS Number739-71-9
Product group Chemicals
Molecular Weight294.43
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Trimipramine [739-71-9]
  • Delivery Days Customer
    10
  • CAS Number
    739-71-9
  • Certification
    Research Use Only
  • Molecular Formula
    C20H26N2
  • Molecular Weight
    294.43
  • Scientific Description
    Trimipramine is a 5-HT receptor antagonist, with pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively. Trimipramine is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 microM, 2.11 microM, 3.72 microM, 8.00 microM, respectively. Trimipramine has vascular activity and anxiolytic efficacy[1][2][3].
  • SMILES
    CC(CN1C2=CC=CC=C2CCC3=C1C=CC=C3)CN(C)C
  • UNSPSC
    12352200