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Trimipramine

HY-B1213A
MedChem Express
CAS Number739-71-9
DownloadMSDS
Product group Chemicals
Molecular Weight294.43
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Trimipramine [739-71-9]
  • Delivery Days Customer
    10
  • CAS Number
    739-71-9
  • Certification
    Research Use Only
  • Molecular Formula
    C20H26N2
  • Molecular Weight
    294.43
  • Scientific Description
    Trimipramine is a 5-HT receptor antagonist, with pK i binding values of 6.39, 8.10, 4.66 for 5-HT 1C , 5-HT 2 and 5-HT 1A , respectively. Trimipramine is also a potent and selective inhibitor targeting human noradrenaline ( hNAT ), serotonin ( hSERT ) and organic cation transporters ( hOCT1 , hOCT2 ) with IC 50 values of 4.99 microM, 2.11 microM, 3.72 microM, 8.00 microM, respectively. Trimipramine has vascular activity and anxiolytic efficacy [1] [2] [3] .
  • SMILES
    CC(CN1C2=CC=CC=C2CCC3=C1C=CC=C3)CN(C)C
  • UNSPSC
    12352200

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