TRIP10 Antibody

Cusabio

TRIP10 Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

TRIP10

thyroid hormone receptor interactor 10

CIP4, HSTP, STOT, STP, TRIP-10, cdc42-interacting protein 4, TR-interacting protein 10, protein Felic, salt tolerant protein, salt tolerator, thyroid receptor-interacting protein 10

Rabbit

IgG

Cdc42-interacting protein 4

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Human

-20°C or -80°C

41116161