Triptolide
S3604
CAS Number38748-32-2
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameTriptolide [38748-32-2]
- Delivery Days Customer9
- CAS Number38748-32-2
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionTriptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-kappaB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.
- Storage Instruction-80°C
- UNSPSC51202000
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