Triptriolide
HY-N15315
Molecular Weight378.42
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameTriptriolide
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC20H26O7
- Molecular Weight378.42
- Scientific DescriptionTriptriolide inhibits Puromycin aminonucleoside PAN (HY-15695)-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3. Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of TAK1-NF-kappaB signaling pathway and upregulation of podocin[1].
- SMILESC[C@@]12[C@@]34[C@]5([C@@H]([C@@](O)([C@@H]([C@]3([H])O4)O)C(C)C)O)[C@@](C[C@@]1([H])C6=C(C(OC6)=O)CC2)([H])O5
- UNSPSC12352200