TrkC antibody [9R22]

GeneTex

TrkC antibody [9R22]

9

WB: 1:500 - 1:1000. IHC-Fr: 1:20 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

9R22

500 ug/ml

Unconjugated

NTRK3

neurotrophic receptor tyrosine kinase 3

ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; tyrosine kinase receptor C

Mouse

IgG2

NT-3 growth factor receptor

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203