Tropisetron-d5 [1220284-86-5]

MedChem Express

Tropisetron-d5 [1220284-86-5]

5

CHEMICAL,detergents_surfactants

Research Use Only

C17H15D5N2O2

289.38

Tropisetron-d5 (SDZ-ICS-930-d5 (free base)) is deuterium labeled Tropisetron. Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT3R antagonists with a Ki of 5.3 nM. Tropisetron is also a partial agonist of alpha7 nicotinic receptor (alpha7 nAChR) with an EC50 of 1.3 microM. In addition, Tropisetron has antitumor and neuroprotective effects[1][2][3][4][5][6][7].

O=C(C1=C([2H])NC2=C1C([2H])=C([2H])C([2H])=C2[2H])O[C@H]3C[C@H]4CC[C@H](N4C)C3

12352005