Tropomyosin 3 antibody
GTX109592
Overview
- SupplierGeneTex
- Product NameTropomyosin 3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.35 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7170
- Target nameTPM3
- Target descriptiontropomyosin 3
- Target synonymsalpha-tropomyosin, slow skeletal; CAPM1; CFTD; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; heat-stable cytoskeletal protein 30 kDa; HEL-189; HEL-S-82p; hscp30; NEM1; OK/SW-cl.5; TM3; TM30; TM30nm; TM5; TM-5; TPM3nu; TPMsk3; TRK; tropomyosin 3 nu; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin-5
- HostRabbit
- IsotypeIgG
- Protein IDP06753
- Protein NameTropomyosin alpha-3 chain
- Scientific DescriptionThis gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Attenuation of LDHA expression in cancer cells leads to redox-dependent alterations in cytoskeletal structure and cell migration. Arseneault R et al., 2013 Sep 28, Cancer LettRead more