TrxR1-IN-1

MedChem Express

TrxR1-IN-1 [3052303-04-2]

14

Research Use Only

C23H18N2O4Se

465.36

TrxR1-IN-1 (Compound 5j) is a TrxR1 inhibitor (IC50: 8.8 microM). TrxR1-IN-1 has anticancer activity, with IC50s of MCF-7 (1.5 microM), HeLa (1.7 microM), BGC-823 (2.4 microM), SW-480 (2.8 microM), A549 (2.1 microM). TrxR1-IN-1 has antioxidant activity, and scavenges DPPH radical[1].

O=C1N(C2=CC=C(CNC(C3=C(C=CC=C3)OC(C)=O)=O)C=C2)[Se]C4=CC=CC=C41

12131703