Trypacidin [1900-29-4]

TargetMol Chemicals

Trypacidin [1900-29-4]

16

1900-29-4

Chemical

Research Use Only

Trypacidin

C18H16O7

344.319

Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 microg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 microg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 microM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1

3 years

COC(=O)C1=CC(=O)C=C(OC)[C@@]11Oc2cc(C)cc(OC)c2C1=O

-20°C

12352200