TS-IN-2

MedChem Express

TS-IN-2 [2945983-00-4]

14

Research Use Only

C18H23N3O4S

377.46

TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 microM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].

S=C1OC(COC2=CC=C(CC=C)C=C2OC)=NN1CN3CCOCC3

12131703