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TSLPR, Mouse (HEK293, Fc)

HY-P70823
MedChem Express
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TSLPR, Mouse (HEK293, Fc)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Gene ID57914
  • Target name
    Crlf2
  • Target description
    cytokine receptor-like factor 2
  • Target synonyms
    CRLM2; cytokine receptor-like factor 2; cytokine receptor-like molecule 2; Ly11; Ly114; lymphocyte antigen 114; T; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin, receptor; Tpte; Tpte2; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2; TSLP receptor; Tslpr; type I cytokine receptor delta 1
  • Scientific Description
    Cytokine receptor-like factor 2 (Crlf2), also known as thymic stromal lymphopoietin (TSLP) receptor, is a receptor for TSLP. Crlf2 can forms a functional complex with TSLP and IL7RA, and overexpression of Crlf2 stimulates cell proliferation through activation of the JAK-STAT pathway. The expression of Crlf2 usually upregulates and mutated in populations of B-progenitor acute lymphoblastic leukemia (B-ALL)[1][2]. TSLPR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TSLPR protein, expressed by HEK293 , with C-hFc labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100