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TTA-A2

HY-111828
MedChem Express
CAS Number953778-63-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.0
Molecular Weight378.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TTA-A2 [953778-63-7]
  • Delivery Days Customer
    10
  • CAS Number
    953778-63-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C20H21F3N2O2
  • Molecular Weight
    378.39
  • Scientific Description
    TTA-A2 is a potent, selective and orally active t-type voltage gated calcium?channel antagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a 1 G) and Cav3.2 (a 1 H) channels with IC 50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy [1] [2] .
  • SMILES
    O=C(N[C@@H](C1=NC=C(OCC(F)(F)F)C=C1)C)CC2=CC=C(C3CC3)C=C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200