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ProductsBack/TTI1 Antibody

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA012188LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA012188LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA012188LA01HU at dilution of 1:100

TTI1 Antibody

CSB-PA012188LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetTTI1

Overview

Supplier
Cusabio
Product Name
TTI1 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID9675
Target name
TTI1
Target description
TELO2 interacting protein 1
Target synonyms
KIAA0406, NEDMIM, smg-10, TELO2-interacting protein 1 homolog, TEL2-interacting protein 1 homolog, Tel two interacting protein 1, smg-10 homolog, nonsense mediated mRNA decay factor
Host
Rabbit
Isotype
IgG
Protein IDO43156
Protein Name
TELO2-interacting protein 1 homolog
Scientific Description
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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