TTK21 [709676-56-2]

MedChem Express

TTK21 [709676-56-2]

10

709676-56-2

Research Use Only

99.39

C17H15ClF3NO2

357.75

TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 passes the blood-brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has beneficial implications for the brain functions of neurogenesis and long-term memory[1].CSP-TTK21 can ameliorate Abeta-impaired long-term potentiation (LTP). CSP-TTK21 may enhance the transcription of genes that promote synaptic health and cognitive function[2]. CSP-TTK21 is orally effective and leads to improvements in motor functions, histone acetylation dynamics in a spinal injury rat model[3].

ClC1=CC=C(C=C1C(F)(F)F)NC(C2=CC=CC=C2OCCC)=O

-20°C,2°C to 8°C

12131703