Tubastatin A

MedChem Express

Tubastatin A [1252003-15-8]

5

1252003-15-8

Research Use Only

98.37

C20H21N3O2

335.40

Tubastatin A is a potent and selective HDAC6 inhibitor with an IC 50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-beta-lactamase domain-containing protein 2 (MBLAC2) .

O=C(NO)C1=CC=C(CN2C3=C(CN(C)CC3)C4=C2C=CC=C4)C=C1

-20°C,2°C to 8°C

12352200