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Tubastatin A (TFA)

HY-13271B
MedChem Express
CAS Number1239262-52-2
DownloadMSDS
Product group Chemicals
Molecular Weight449.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tubastatin A (TFA) [1239262-52-2]
  • Delivery Days Customer
    14
  • CAS Number
    1239262-52-2
  • Certification
    Research Use Only
  • Molecular Formula
    C22H22F3N3O4
  • Molecular Weight
    449.42
  • Scientific Description
    Tubastatin A (TSA) TFA is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A TFA also inhibits HDAC10 and metallo-beta-lactamase domain-containing protein 2 (MBLAC2).
  • SMILES
    O=C(NO)C1=CC=C(CN2C3=C(CN(C)CC3)C4=C2C=CC=C4)C=C1.O=C(O)C(F)(F)F
  • UNSPSC
    12352200

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