Tubulin inhibitor 21

MedChem Express

Tubulin inhibitor 21

10

Research Use Only

C28H25N3O4S

499.58

Tubulin inhibitor 21 (compound 6f), a chalcone- and melatonin- based hybrid, is a potent tubulin inhibitor. Tubulin inhibitor 21 induces a remarkable cytotoxic activity toward SW480 cells (IC50=0.26 microM) with lower effect against nonmalignant cells[1].

O=C(C1=CC=C(C=C1)OCCCSC2=NN=C(O2)CCC3=CNC4=C3C=CC=C4)/C=C/C5=CC=CO5

12352200