Tubulin inhibitor 35 [2247047-77-2]
HY-155073
CAS Number2247047-77-2
Product group Chemicals
Molecular Weight331.41
Overview
- SupplierMedChem Express
- Product NameTubulin inhibitor 35 [2247047-77-2]
- Delivery Days Customer14
- CAS Number2247047-77-2
- CertificationResearch Use Only
- Molecular FormulaC21H21N3O
- Molecular Weight331.41
- Scientific DescriptionTubulin inhibitor 35 (compound 6b) is a dual inhibitor of topoisomerase I (IC50=~50 microM) and tubulin polymerization (IC50=5.69 microM). Tubulin inhibitor 35 inhibits migration and invasion of MGC-803 and RKO cell lines, and induces apoptosis via arresting cell cycle at G2/M phase. Tubulin inhibitor 35 exhibis potent efficacy in gastrointestinal tumor inhibiton (inhibits MGC-803 (IC50=0.09 microM) and RKO (IC50=0.2 microM) cell lines)[1].
- SMILESO=C(N(CCC1=C2NC3=C1C=CC=C3)C2N4CCC)C5=C4C=CC=C5
- UNSPSC12352200