Tubulin inhibitor 36

MedChem Express

Tubulin inhibitor 36

14

Research Use Only

C16H13ClN6S

356.83

Tubulin inhibitor 36 (Compound 10) is a novel and potent tubulin inhibitor and inhibits the polymerization of microtubular protein then induces apoptosis with an IC50 value of 1.5+/-0.1 microM. Tubulin inhibitor 36 (Compound 10) has significant anti-mitotic effect and exhibits activities against glioblastoma cells. Tubulin inhibitor 36 (Compound 10) has anti-tumor effects and can be used for glioblastoma multiforme (GBM) research[1].

CN1C=CC2=C1C=CC(N3N=NN=C3C4=CC(Cl)=NC(SC)=C4)=C2

12131703