Tubulin polymerization-IN-16 [2296731-38-7]

MedChem Express

Tubulin polymerization-IN-16 [2296731-38-7]

10

2296731-38-7

Research Use Only

C24H27N5O5

465.50

Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC50 values of 0.084-0.221 microM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells[1].

COC1=CC(C(C2=NN(N=C2N3CCN(CC3)C(C)=O)C4=CC=CC=C4)=O)=CC(OC)=C1OC

12131703