Tubulin polymerization-IN-26 [2490291-68-2]

MedChem Express

Tubulin polymerization-IN-26 [2490291-68-2]

10

2490291-68-2

Research Use Only

C25H23N3O2

397.47

Tubulin polymerization-IN-26 (compound 12h) can inhibit the polymerization of microtubulin by binding to the colchicine binding site of microtubulin with an IC50 value of 4.64 microM. Tubulin polymerization-IN-26 can induce apoptosis and inhibit cell metastasis or migration, and can be used as a potential compound for lung cancer research[1].

O=C(NC1=CC=CC=C1C2=NC3=CC(C)=CC=C3N2)/C=C/C4=CC=CC=C4OCC

12131703