Tubulin polymerization-IN-30 [2521560-46-1]
HY-147947
CAS Number2521560-46-1
Product group Chemicals
Molecular Weight407.47
Overview
- SupplierMedChem Express
- Product NameTubulin polymerization-IN-30 [2521560-46-1]
- Delivery Days Customer10
- CAS Number2521560-46-1
- CertificationResearch Use Only
- Molecular FormulaC22H25N5O3
- Molecular Weight407.47
- Scientific DescriptionTubulin polymerization-IN-30 (compound 6e) is a potent Tubulin polymerization inhibitor. Tubulin polymerization-IN-30 is a colchicine binding site inhibitor. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits the high potency against the cancer cell lines including SGC-7901, A549 and HeLa, with IC50 values of 2.16, 2.21, and 0.403 microM[1].
- SMILESO=C(C1=NN=C(C)N1C2=CC=CC=C2)N3CCN(C4=CC(OC)=CC(OC)=C4)CC3
- UNSPSC12131703