Tubulin polymerization-IN-6

MedChem Express

Tubulin polymerization-IN-6 [2768613-52-9]

10

Research Use Only

C19H21NO7

375.37

Tubulin polymerization-IN-6 (compound 5f) is a potent tubulin polymerization inhibitor, with an IC50 of 1.09 microM. Tubulin polymerization-IN-6 inhibits cell migration and tube formation and contributes to the anti-angiogenesis. Tubulin polymerization-IN-6 can greatly inhibit tumor growth on HT29 xenograft Balb/c nude mice[1].

COC(C1=CC2=C(OCCO2)C=C1NC3=CC(OC)=C(C(OC)=C3)OC)=O

12131703