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Tubulin polymerization-IN-9 [2485020-93-5]

HY-146718
MedChem Express
CAS Number2485020-93-5
Product group Chemicals
Molecular Weight420.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tubulin polymerization-IN-9 [2485020-93-5]
  • Delivery Days Customer
    10
  • CAS Number
    2485020-93-5
  • Certification
    Research Use Only
  • Molecular Formula
    C19H19NO5Se
  • Molecular Weight
    420.32
  • Scientific Description
    Tubulin polymerization-IN-9 is a potent tubulin inhibitor with IC50 of 1.82 microM. Tubulin polymerization-IN-9 causes cell cycle arrest at G2/M phase, and induces cell apoptosis and depolarized mitochondria of K562 cells. Tubulin polymerization-IN-9 has potent anti-vascular and antitumor activities[1].
  • SMILES
    COC1=CC([Se](=O)(/C=C/C2=CC=CC3=C2C=CN3)=O)=CC(OC)=C1OC
  • UNSPSC
    12131703