TUG-499 [1206629-08-4]

MedChem Express

TUG-499 [1206629-08-4]

5

1206629-08-4

Research Use Only

99.78

C16H11Cl2NO2

320.17

TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) (Free Fatty Acid Receptor) agonist with a pEC50 of 7.39. TUG-499 exhibits >100-fold selectivity over the related receptors FFA2, FFA3, and the nuclear receptor PPARgamma and other diverse receptors, ion channels, and transporters. TUG-499 can be used for the research of type 2 diabetes[1]. TUG-499 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(O)CCC1=CC=C(C#CC2=CC(Cl)=NC(Cl)=C2)C=C1

-20°C,2°C to 8°C

12131703