TUG-770 [1402601-82-4]

MedChem Express

TUG-770 [1402601-82-4]

10

1402601-82-4

Research Use Only

99.07

C19H14FNO2

307.32

TUG-770 is a potent, selective and orally active GPR40/FFA1 agonist with an EC50 of 6 nM for human FFA1. TUG-770 shows a high selectivity for FFA1 over FFA2, FFA3, FFA4, PPARgamma, other receptors, transporters, and enzymes. TUG-770 can be uesd for type 2 diabetes research[1]. TUG-770 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

FC1=C(CCC(O)=O)C=CC(C#CC2=C(CC#N)C=CC=C2)=C1

-20°C,2°C to 8°C

12352200